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Hall of Fame

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Hall of Fame

No. Name Title Supervisor
2018      
214 Heidi Kemiläinen
HSD17B12 – an enzyme with a role in embryonic development, normal ovarian function and cancer Leena Strauss, Matti Poutanen
2017      
213 Paulina Budzynska Regulation of B cell development by transcription factors IRF4 and BACH2 Olli Lassila
212 Dunkel Johannes Heterogeneity of oral cavity cancer with special attention to immune function of CLEVER-1 Sirpa Jalkanen, Heikki Irjala
211 Marek Budzynski Stress Management: Multilayer Regulation of the Heat Shock Response

John Eriksson

210 Anna Knittle Regulation of ErbB4 signaling by post-translational modifications Klaus Elenius
209 Otto Kauko  A systems biology analysis of PP2A functions in cancer cells Jukka Westermarck
2016      
208 Hanna Korhonen The essential role of DICER in spermatogenesis and male fertility Noora Kotaja
207 Jemiina Salo The role of DbpA and B adhesins in the pathogenesis of Lyme borreliosis Jukka Hytönen
206 Ashutosh Trehan Assay development and study of a mutation affecting gonadotropin action Ilpo Huhtaniemi, Adolfo Rivero-Müller
205 Jonna Alanko Integrin traffic and signalling - from plasma membrane to endosomes Johanna Ivaska
204 Riina Kaukonen Filopodia and stromal extracellular matrix as regulators of cancer cell invasion and growth Johanna Ivaska
203 Amanpreet Kaur The role of PME-1 in cancer: Therapeutic implications    Jukka Westermarck
202 Senthil Palani CLEVER-1 as an immune suppressive molecule Sirpa Jalkanen
201 Kalle Sipilä Unconventional integrin-ligand interactions Jyrki Heino
200 Julia Misiorek The role of keratin intermediate filaments in the colon epithelial cells Diana Toivola
199 Maja Solman Nanoclustering augmentation – a novel mechanism of
Ras activation in cancer
Daniel Abankwa
2015      
198 Emmi Rotgers Retinoblastoma protein and E2F transcription factors in testicular development and adult spermatogenesis Jorma Toppari
197 Pekka Heikkinen Modulation of TGF-β Signaling by Hypoxia Panu Jaakkola
196 Reetta Virtakoivu From epithelial to mesenchymal: regulation of invasive cancer cell motility Johanna Ivaska
195 Matteo Da Ros The Chromatoid body entourage: Molecular characterization of the Chromatoid body-associated cytoplasmic vesicles Noora Kotaja
194 Muhammad Nadeem Asghar Roles of keratins in intestinal health and disease Diana Toivola
193 Marika Sjöqvist Networking Notch – regulation of Notch traffic and signaling crosstalk John Eriksson
192 Julia Lindqvist To divide or differentiate? Nestin-mediated regulation of Cdk5 in cell fate decisions John Eriksson
191 Mirkka Heinonen Players of Th-cell differentiation and immune dysregulation - focus on GIMAP family  genes Riitta Lahesmaa, Tiina Henttinen
2014      
190 Kari Kurppa ERBB4 mutations in cancer and amyotrophic lateral sclerosis Klaus Elenius
189 Ida Björkgren Novel genes and regulatory systems in epididymal differentiation and sperm maturation of the mouse Matti Poutanen, Petra Sipilä
188 Henna Kallionpää Gene Regulation in the Human Immune System - Signatures of Th2 Cell Differentiation, Type 1 Diabetes, and Intrauterine Immune Adaptation Riitta Lahesmaa
187 Alexandra Elsing Regulation of HSF2 and its Function in Mitosis Lea Sistonen
186 Anniina Vihervaara Choosing the target loci: Heat shock factors HSF1 and HSF2 as regulators of cell stress and development Lea Sistonen
185 Susann Björk Cell model systems in characterizing alpha2-adrenoceptors as drug targets Mika Scheinin
184 Claire Hyder Tuning Cell Motility – Roles of Nestin and Vimentin in Cancer Cell Invasion and Motility John Eriksson
183 Mirkka Hirvonen Vesicular trafficking in Osteoclasts Kalervo Väänänen
2013      
182 Oliver Meikar Chromatoid body mediated RNA regulation in mouse male germline Noora Kotaja
181 Minna Toivonen Fluorescence-based imaging of cellular defect in lysinuric protein intolerance (LPI) Juha Mykkänen,
Olli Simell
180 Tomoko Asaoka Regulation of cell fate by c-FLIP phosphorylation John Eriksson
179 Nelly Rahkonen Regulation of self-renewal and detection of karyotypic changes of pluripotent human embryonic stem cells Riitta Lahesmaa, Riikka Lund
178 Michaela Nygårdas Herpes simplex virus type 1 (HSV-1) pathogenesis and HSV gene therapy of experimental autoimmune encephalomyelitis Veijo Hukkanen
177 Anni Laine The Role of an Oncoprotein CIP2A in Breast Cancer Jukka Westermarck
176 Antti Arjonen Integrins on the move Johanna Ivaska
175 Johannes Keuschnigg PV-1: Leukocyte trafficking molecule and vascular marker Sirpa Jalkanen
174 Outi Heikkilä Receptors and endocytosis of coxsackievirus A9 Petri Susi
173 Tiina Kelkka Reactive Oxygen Species in Inflammation Rikard Holmdahl, Malin Hultqvist
172 Soile Tuomela System-level characterization of Th2 cell development and immune cell responses to ZnO and TiO2 nanoparticles Riitta Lahesmaa
171 Ilkka Paatero Novel Functions of ErB4 and NRG-1 in Development and Cancer Klaus Elenius
170 Gunilla Högnäs Integrins in Tumorigenesis and Cancer Cell Invasion Johanna Ivaska
2012      
169 Matti Lahti The structure and function of αI domains in collagen receptor and leukocyte integrins

Jyrki Heino,
Jarmo Käpylä

168 Marika Karikoski Leukocyte Trafficking: a Special Focus on VAP-1 and CLEVER-1 Sirpa Jalkanen, Heikki Irjala
167 Elisa Närvä Pluripotency and Genetic Stability of Human Pluripotent Stem Cells Riitta Lahesmaa
166 Eeva-Mari Jouhilahti The Roots of Neurofibromas in Neurofibromatosis 1 - A Question of Multipotency, Differentiation and Hiding Juha Peltonen, SIrkku Peltonen
165 Minna Niemelä Identification and characterization of CIP2A as a novel oncogenic inhibitor of PP2A Jukka Westermarck
164 Anna-Leena Salmela The Spindle Assembly Checkpoint as a Drug Target – Novel Small-Molecule Inhibitors of Aurora Kinases Marko Kallio
163 Christoffer Löf TR(i)P, TR(i)P, HOORAY: New functions for TRPC2 and TRPC3 Kid Törnquist
162 Ilpo Koskivirta Generation and Characterization of Knockout Mice and Analysis of Patient Material Demonstrates a Role for Tissue Inhibitor of Metalloproteinases 4 (Timp4) in the Cardiovascular System and Tumor Metastasis Eero Vuorio,
Hannu Järveläinen
161 Juho Joutsa Neurobiology of pathological gambling - Brain imaging and epidemiological studies Valtteri Kaasinen, Juha O. Rinne
160 Juho-Antti Mäkelä Identification and characterization of new genes and pathways regulating spermatogonial cell fate
Jorma Toppari
159 Mervi Toriseva The regulation and function of collagenase-3 (MMP-13) in cutaneous wound healing and squamous cell carcinoma Veli-Matti Kähäri
2011      
158 Teemu Kallonen Evolution of Bordetella pertussis post vaccination
Qiushui He, Jussi Mertsola
157 Ville Veikkolainen Regulation of cell growth, death, and polarization by ERBB4 Klaus Elenius
156 Heikki Turunen Characterization of novel genes predominantly expressed in the epididymis – from genomic analyses to genetically modified mice Matti Poutanen, Ilpo Huhtaniemi
155 Johanna Björk Role and regulatory mechanisms of heat shock factor 2 Lea Sistonen
154 Juha Järvelä Kainic acid-induced seizures: inflammation and excitotoxic neuronal damage in the developing rat hippocampus Irma Holopainen
153 Katri Kivinen Nuclear matrix in apoptotic cell death and cell proliferation. The role of Nuclear Mitotic Apparatus (NuMA) Protein Markku Kallajoki
152 Terhi Jokilehto The Cellular Oxygen Sensor PHD2 in Cancer Growth Panu Jaakkola
151 Kati Tarkkonen Fibroblast Growth Factor 8 and its Receptors in the Growth and Angiogenesis of Experimental Breast Cancer with Special Reference to Thrombospondin-1 as a Novel Target Gene For FGF-8 Pirkko Härkönen
150 Jonna Nevo Novel Players in the Integrin Signaling Orchestra: TCPTP and MDG Johanna Ivaska
2010
149 Jukka Alinikula Regulation of B cell Gene Expression and Function by Ikaros, Helios and Bcl6 Olli Lassila
148 Hanna Taipaleenmäki Factors Regulating Chondrogenic Differentiation Anna-Marja Säämänen
147 Raine Toivonen Targeting Adenoviral Gene Therapy Vectors to Head and Neck Squamous Cell Carcinoma and Heart Mikko Savontaus
146 Karoliina Vuoriluoto Anchor or Accelerate – A Study on Cancer Cell Adhesion and Motility Johanna Ivaska
145 Saara Tuomi

The Integrin Tail: A Tale of Cell Motility and Division

Johanna Ivaska
144 Juha Laurila Therapeutic Properties of Superoxide Dismutase 3 and Mesenchymal Stromal Cells in Peripheral Ischemia Mikko Laukkanen, Sirpa Jalkanen
143 Hanna-Mari Pallari

Dynamic Interplay Between the Intermediate Filament Protein Nestin and Cyclin-dependent Kinase 5

John Eriksson
142 Johanna Ahlskog Regulation of Heat Shock Transcription Factors by Ubiquitin and Ubiquitin-like Modifiers

Lea Sistonen
141 Pekka Kohonen Genetic regulatory networks in avian B cells

Olli Lassila
140 Nina Bergelin Interactions Between Sphingosine 1-Phosphate and Vascular Endothelial Growt Factor Signaling in Thyroid Carcinoma Cells Kid Törnqvist
139 Anton Sandqvist HSF1-HSF2 heterotrimerization as a transcriptional switch and miR-18 mediated regulation of HSF2 Lea Sistonen
138 Henri Blomster Cellular Regulation of SUMO Modification by Alternative Targeting Mechanisms Lea Sistonen
137 Riikka Riihonen Acid-Base Balance and Oxidative Metabolism in Calcified Tissues Tiina Laitala-Leinonen
136 Maija Hollmén Role of ErbB2 and ErbB4 in cancer growth, prognosis and as targets for immunotherapy Klaus Elenius
2009
135 Malin Åkerfelt Novel Target Genes for Heat Shock Factor 1 and 2 in Development

Lea Sistonen
134 Aura Kaunisto Differential Regulation of c-FLIP Isoforms Through Post-translational Modifications John Eriksson
133 Taija Saloniemi Role of human hydroxysteroid (17β) dehydrogenase type 1 (HSD17B1) in steroid-dependent diseases in females ‒novel indications for HSD17B1 inhibitors. Phenotypic analysis of transgenic mice overexpressing human HSD17B1 Matti Poutanen
132 Mirja Nurmio Cancer therapy-related toxicity in the immature testis Jorma Toppari, Kirsi Jahnukainen
131 Johanna Lempainen Virus Infections in Early Childhood, Cow’s Milk Formula Exposure and Genetic Predisposition in the Development of Diabetes-Associated Autoimmunity Jorma Ilonen
130 Julius Anckar Multisite post-translational regulation of heat shock transcription factors Lea Sistonen
129 Teijo Pellinen Beta 1 integrin regulation Johanna Ivaska
128 Kaisa Auvinen VAP-1 in leukocyte trafficking Sirpa Jalkanen
127 Pauliina Hartiala Immune Evasion by Borrelia burgdorferi – With Special Reference to CD38-mediated Chemotaxis of Neutrophils and Dendritic Cells Matti K. Viljanen,
Jukka Hytönen
2008      
126 Nina Westerlund Cytoskeletar effectors of JNK in regulating nerve cell architecture and migration Eleanor Coffey
125 Leena Ahonen Mitotic Regulation by Polo-Like Kinase 1 and the Chromosomal Passenger Complex Marko Kallio
124 Petteri Ahtiainen Regulating Mechanisms of Gonadal and Pituitary Tumorigenesis in Mice Producing Human Chorionic Gonadotropin Ilpo Huhtaniemi
123 Thomas Söderström Regulation of Death Receptor-Mediated Apoptosis in T-cells John Eriksson
122 Aino Rönnblad Transgenic mouse models for studying the abnormal regulation and endocrine functions of prolactin and progesterone Matti Poutanen
121 Anu Kallio The effects of Selective Estrogen Receptor Modulators on the death of breast cancer cells and osteoblastic cells Pirkko Härkönen
120 Maija Valta Fibroblast growth factor 8 in the progression of hormonal cancer, bone metastasis and cancer-associated bone formation Pirkko Härkönen
119 Erika Iivanainen ErbB ligands in angiogenesis Klaus Elenius
2007
118 Maria Sundvall Signaling of ErbB4 Isoforms in Cancer Klaus Elenius
117 Kirsi Rautajoki Regulatory mechanisms involved in Th2 cell differentiation. A proteomics approach Riitta Lahesmaa
116 Maritta Löytömäki Immunopathogenesis of Asthma and Atopic Diseases – Specific role of a selected panel of genes in human T helper cell differentiation Riitta Lahesmaa
115 Annika Meinander Regulation of Death Receptor Responses by Hyperthermia John Eriksson
114 Markus Vähä-Koskela Construction and characterization of a replication-competent expression vector based on avirulent Semliki Forest virus Ari Hinkkanen
113 Elli Narvi Aiolos and B Cells Olli Lassila
2006
112 Kalle-Pekka Nera Regulation of B cell function by Pax5 and Ikaros Olli Lassila
111 Tomas Blom Sphingolipid-mediated regulation of cellular calcium signaling and survival Kid Törnquist
110 Päivi Östling Characterization of heat shock factor 2 as a transcriptional regulator Lea Sistonen
109 Arto Pulliainen Bacterial H2O2 resistance in the absence of catalase: from gene identification to structure-functional understanding in streptococci
Jukka Finné
108 Jenni Jalkanen Discovery and characterization of novel genes expressed in the mouse epididymis Matti Poutanen, Ilpo Huhtaniemi
107 Anu Puomila Genetics of Monosymptomatic Hereditary Optic Neuropathies Kirsi Huoponen, Eeva Nikoskelainen
106 Emmi Ylikoski Novel Mechanisms involved in Human T Helper 1 Cell Differentiation Riitta Lahesmaa
105 Jutta Peltoniemi Immunomodulative treatment and experimental virus infections of the central nervous system Veijo Hukkanen, Juha-Pekka Erälinna
104 Mikael Maksimow Dendritic Cell Vaccination in the Induction of Immunity or Tolerance Arno Hänninen
103 Jussi Niemelä Control of Inflammation, Leukocyte Trafficking and Endothelial Barrier Function by CD73
Laura Airas, Sirpa Jalkanen
102 Melissa Junttila Regulation of mitogen-activated protein kinase pathways in cancer Veli-Matti Kähäri, Jukka Westermarck
101 Tuomas Mirtti Tissue Markers and Molecular Mechanisms in Pathogenesis and Clinical Progression of Prostate Cancer Kalle Alanen, Markku Kallajoki, Jyrki Heino
100 Suvi-Katri Leivonen The Role of Smad and Mitogen-Activated Protein Kinase Signaling in Transforming Growth Factor-beta-Induced Extracellular Matrix Remodeling Veli-Matti Kähäri
2005
99 Terhi Heino Osteocytes as Regulators of Bone Resorption
and Bone Formation
Kalervo Väänänen
98 Teemu Junttila Signaling Mechanisms and Prognostic Significance of ErbB4 Isoforms in Cancer Klaus Elenius
97 Teija Aho Pim kinases in regulation of hematopoietic cell fate Päivi Koskinen
96 Tommi Ahonen Characterization of signal transducer and activator of transcription 5 (STAT5) -dependent survival of prostate cancer cells Pirkko Härkönen & Marja T. Nevalainen
95 Kirsi Joronen Studies on the role of matrix metalloproteinases and their inhibitors in inflammatory arthritides in the mouse Eero Vuorio,
Veli-Matti Kähäri
94 Kaisa Ivaska Osteocalcin. Novel insights into the use of osteocalcin as a determinant of bone metabolism Kalervo Väänänen
93 Minna Poukkula Staying Alive. Modulation of TRAIL-induced Apoptosis by Ubiquitination and Phosphorylation John Eriksson
92 Jori Ruuskanen Comparative molecular and functional analysis of human and zebrafish alpha2-adrenoceptors Mika Scheinin

91

Ville Kytö

Fatal myocarditis with special reference to viral etiology and cardiomyocyte apoptosis

Liisa-Maria Voipio-Pulkki

2004
90 Marina Merne Effects of smokeless tobacco on oral mucosa in vitro and in vivo Stina Syrjänen
89 Pekka Taimen NuMA in Cell Proliferation and Programmed Cell Death Markku Kallajoki
88 Marko Kaleva Congenital cryptochidism. Studies on prevalence, etiology and treatment of cryptochidism Jorma Toppari
87 Petra Furu The Pathogenesis of Experimental Autoimmune Encephalomyelitis of the Balb/c Mouse: Role of lymphokines and matrix metalloproteinases Ari Hinkkanen
86 Riku Kiviranta The role of cathepsin K in bone remodeling. Generation of transgenic, knockout and conditional knockout mouse models Eero Vuorio
85 Vilhelmiina Parikka Regulation of bone cell function by 17beta-estradiol and SERMs Kalervo Väänänen
84 Pasi Koskimies The Function and Regulation of the Insulin-like 3 (Insl3) Gene Ilpo Huhtaniemi
83 Saku Sinkkonen Imaging and properties of extrasynaptic GABA(A) receptors in the brain Esa Korpi
82

Pia Suonpää

Differentiation of hematopoietic stem cells into B lymphocytes Olli Lassila
81 Katriina Peltola Signaling in cancer: Pim-1 kinase and its partners Päivi Koskinen
80 Sanna Oksjoki Connective tissue turnover in normal and polycystic ovaries Leena Anttila & Eero Vuorio
79 Hannu Turpeinen Contribution of Immunoregulatory Genes to Genetic Susceptibility to Type 1 Diabetes - Association and Linkage Studies Jorma Ilonen
78 Milja Möttönen Functional regulation of antigen-presenting cells and T cells in rheumatoid arthritis Olli Lassila
77 Riikka Lund Identification of novel genes involved in the early differentiation of Th1 and Th2 cells Riitta Lahesmaa
76 Pekka Koistinen AlphaV integrins in cancer Jyrki Heino
75 Otto Rahkonen Extracellular Matrix and Its Turnover in Murine Cardiovascular System in Normal and Transgenic Mice Eero Jokinen and Eero Vuorio
74 Eeva Broberg Herpes Simplex Virus Type 1 (HSV-1) Infection and HSV-Based Vectors in Treatment of Experimental Autoimmune Encephalomyelitis in BALB/c Mice Veijo Hukkanen
2003
73 Tao He Post-Translational Modifications of
Intermediate Filament Proteins - Implications for Cell Signaling
John Eriksson
72 Sanna-Mari Maula Adhesion molecules in the dissemination and the prognosis of cancer: special reference to CD44, VAP-1 and LYVE-1 Sirpa Jalkanen and Raija Ristamäki
71 Ville Hietakangas Posttranslational regulation involved in HSF1 - and HSF2 -mediated transcription Lea Sistonen
70 Jenni Heikkinen Immune regulation in the human decidua Olli Lassila and Anna Alanen
69 Minna Tuittila The role of the replicase proteins in Semliki Forest virus neurovirulence Ari Hinkkanen
68 Heli Harvala Molecular Pathogenesis of Coxsackievirus Infections. The Specific Role of the RGD Motif in the CAV Timo Hyypiä

67

Kimmo Koskela Molecular and functional chracterization of avian gamma delta T cells and B cells Olli Lassila
66 Johanna Mäkinen Molecular characterization and evolution of Bordetella Pertussis and Bordetella Parapertussis, with special reference to pertactin and pertussis toxin antigens Matti Viljanen, Jussi Mertsola and Qiushui He
65 Maija-Liisa Kalliomäki Expression and regulation of two RFamide peptide genes in the rat Pertti Panula
64 Stefanie Tran Modulation of death receptor-mediated apoptosis by mitogen and stress-induced signalling John Eriksson
63 Petra Sipilä Generation and Use of Transgenic Mice and Mouse Epididymal Epithelial Cell Lines in Studying the Role of Epididymis in Sperm Maturation Matti Poutanen and Ilpo Huhtaniemi
62 Eeva-Marja Rainio Role and Regulation of Pim Kinases in Lymphocytes Päivi Koskinen
61 Tuire Olli-Lähdesmäki Cellular Regulation of Human a2-Adrenoceptors; Studies on Receptor Targeting, Trafficking and Signalling Mika Scheinin
60 Riikka Ihalin Horseradish Peroxidase – Iodide System; a Potential Antibacterial Agent against Periodontal Pathogens in Human Saliva Jorma Tenovuo
59 Kimmo Salminen Enteroviruses and type 1 Diabetes. Evaluation in Finnish Prospective Series Heikki Hyöty
58 Ilkka Jaakkola Lymphocyte Traffic and Adhesion Receptors in the Pancreas and the Gut: Special Emphasis on Autoimmune Diabetes Sirpa Jalkanen and Arno Hänninen

57

Sami Ventelä

Regulation of Spermatogenesis: Differentation of GFP-labeled Stem Cells and the Function of Cytoplasmic Bridges

Martti Parvinen

2002
56 Tina Lozada Brain Histamine in the Regulation of Mammalian Hibernation Pertti Panula
55 Heikki Irjala An Immunotherapeutic Approach to Cancer of the Head and Neck Sirpa Jalkanen and Reidar Grenman
54 Matti Ahonen Characterization of Tumor Suppressor Effect of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) Veli-Matti Kähäri
53 Juha-Pekka Pursiheimo Protein Kinase A: Regulator of Growth Factor-Induced Responses Markku Jalkanen
52 Risto Ala-aho Human Collagenase-3 (MMP-13) in Tumor Growth and Invasion Veli-Matti Kähäri
51 Tommi Paukku Gene Transfer Studies in Transgenic Mouse Gonadal and Adrenocortical Tumor Cells Ilpo Huhtaniemi
50 Jukka Kero Gonadal and Extragonadal Actions of Chronically Elevated Luteinizing Hormone Secretion in Transgenic Mice Ilpo Huhtaniemi
2001
49 Cecilia
Sahlgren
Phosphorylation-Mediated Regulation of the Intermediate Filament Protein Nestin John Eriksson
48 Maria Pajunen Molecular Analysis of Yersinia Enterocolitica Serotype O:3 –Specific Bacteriophage fYeO3-12 Mikael Skurnik
47 Tiina
Henttinen
Role of Soluble Mediators in Leukocyte Activation and Adhesion to the Endothelium: Special Emphasis on Cytokine and Purine Mediated Pathways Sirpa Jalkanen
46 Oleg Anichtchik Histaminergic regulation of the nigrostriatal system in the Parkinson's disease and the rat model of parkinsonism Pertti Panula
45 Kati Härkönen  Genetic Aspects in Andrology – Studies on Sperm Chromosomes, Y Choromosome Microdeletions and Androgen Receptor Polymorphism Jaana Lähdetie
44  Anne West  Expression of pRb and the p53-Inducible Genes p21, Gadd45, mdm2 and Cyclin G During Spermatogenesis – With Special Reference to the DNA Damage Checkpoint in G1 Phase of Spermatocytes Jaana Lähdetie
43  Sami Tohka Leukocyte Adhesion to Endothelium In Vitro and In Vivo. Role of Vascular Adhesion Protein-1 (VAP-1) Sirpa Jalkanen
42 Mirva Söderström Human Chondrosarcoma. A Molecular Biologic, Immunohistologic and Epidemiologic Study on Finnish Patients Eero Vuorio and Hannu Aro
41 Egle Simelyte What Factors Determine Arthritogenicity of Bacterial Cell Wall? Experimental Study With Eubacterium and Lactobacillus Species Paavo Toivanen
40 Tero-Pekka
Alastalo
Cross-Talk Between Heat Shock Transcription Factors 1 and 2 Suggests A Novel Control Mechanism in The Cellular Stress Response Lea Sistonen
39 Johanna
Ruohola
Angiogenic Growth Factors in the Hormone Regulation of Breast Cancer Growth Pirkko Härkönen
38 Jussi
Liippo
Ikaros and Aiolos transcription factors in early lymphopoiesis Olli Lassila
37 Hannele
Uusitalo
Induction of Bone Repair by Bone Morphogenetic Protein-2 Using Adenovirus-Mediated Gene Transfer Eero Vuorio and Hannu Aro
2000
36 Niina
Reunanen
Mitogen-activated protein kinases and extracellular matrix formation. Studies on the regulation of type I collagen, decorin and matrix metalloproteinases-1, -3 and -19 expression in human dermal fibroblasts Veli-Matti Kähäri
35 Heli
Salminen
A Transgenic Mouse Model for Osteoarthritis Eero Vuorio
34 Christel
Nilsson
A Common Genetic Variant of Luteinizing Hormone Ilpo Huhtaniemi and Kim Petterson
33 Carina
Holmberg
Phosphorylation-mediated Regulation of Heat Shock Transcription Factor 1 Lea Sistonen
32 Matti
Karvonen
Leucine 7 to Proline 7 Polymorphism in the
Preproneuropeptide Y Identification of a Novel Genetic Marker for Cardiovascular Disease Risk
Markku Koulu and Ullamari Pesonen
31 Markus 
Halminen
Cytokine Messages Detected and Analysed in Type 1 Diabetes  Jorma Ilonen
30 Virve
Luukkaa
The role of reproductive hormones in the regulation of the ob gene and leptin Risto Huupponen
29 Lila
Pirkkala
Differential Functions of Heat Shock Transcription Factors 1 and 2 Lea Sistonen
28 Tim
Holmström
The role of mitogen activated protein kinase p44/42 in FAS-mediated apoptosis John Eriksson
27 Marjo
Pihlavisto
Characterization of Alpha-2-Adrenoceptor Activation - Functional Assays Based on Transfected Cells Mika Scheinin
26 Janne
Komi
The Effect of Antiestrogens on Antigen Presenting Cells and T Cells Olli Lassila
25 Jari
Jalava
Molecular Detection and Identification of Bacteria Based on PCR and rRNA Phylogeny Paavo Toivanen
24 Laura 
Ravanti
Regulation of the Expression of Human Collagenase-3 (MMP-13) - Implications for Wound Repair and Dermal Fibrosis Veli-Matti Kähäri
23 Kimmo 
Jaakkola
Vascular Adhesion Protein-1 as a Target for Anti-Adhesive Therapy and Inflammation Diagnostics Sirpa Jalkanen
22 Johanna
Ivaska
Cellular Collagen Receptors - Characterization of Specific Ligand Recognition and Signal Transduction Mechanisms
"Mandatum Biotech Prize 2000"
Jyrki Heino
21 Sirpa
Juhela
Type 1 Diabetes and Cellular Immune Response to Enteroviruses Jorma Ilonen
1999
20 Juho 
Rantakokko
Murine Cathepsin K: cDNA and Genomic Cloning and Role in Development of Experimental Osteoporosis Eero Vuorio and Hannu Aro
19 Esa-Pekka 
Pälvimäki 
Interactions of Antidepressant Drugs with Serotonin 5-HT2c Receptors Jarmo Hietala
18 Kaisa 
Katevuo 
ChT1 and T Cell Development Olli Vainio
17 Sergei 
Nejentsev 
Dissection of HLA-linked Type 1 Diabetes - Associated Genes and Use of HLA Markers for Type 1 Diabetes Prediction Jorma Ilonen
16 Tiina 
Pohjalainen 
Variability in Striatal Dopamine D2 Receptor Binding Characteristics In Vivo: Role of Age, Sex and Genetic Factors Jarmo Hietala and Erkki Syvälahti
15 Pasi 
Huttunen 
Molecular Pathogenesis of Echovirus 1 Infection Timo Hyypiä
1998
14 Eriika Savontaus Anti-Obesity Effects of Adrenergic Drugs Activating Thermogenesis in Brown Adipose Tissue Risto Huupponen and Markku Koulu
13 Terhi Lehtinen Integrin Type Collagen Receptors as Regulators of Matrix Related Alterations in Cell Behavior and Gene Expression Jyrki Heino
12 Nina Johansson Human Collagenase-3 (MMP-13) in Development and Malignant Transformation Veli-Matti Kähäri
11 Petri Bono Lymphocyte-Endothelial Cell Interactions: Molecular Analysis of Vascular Adhesion Protein 1 (VAP-1) Sirpa Jalkanen
10 Varpu Kainulainen Syndecans in Tissue Injury Markku Jalkanen
9 Jorma Määttä Experimental Autoimmune Encephalomyelitis of the BALB/c Mouse Ari Hinkkanen
8 Miia Lampisuo Embryonic Development of Avian Lymphocyte Progenitors Olli Lassila
7 Anna-Maija Kujari Expression and Regulation of Adhesion Molecules in Inflammation Sirpa Jalkanen
6 Maria Grazia Santagati Virulence Determinants of Semliki Forest Virus Aimo Salmi and Ari Hinkkanen
5 Tiina Santonen Genotoxicity in Male Germ Cells. Effects of Mutagens on Spermatid Micronuclei, DNA Synthesis, p53 Expression and Apoptosis in Rat Testis Jaana Lähdetie
1997
4 Jukka Westermarck Transcriptional Regulation of Fibroblast Collagenase (MMP-1) Gene Expression Veli-Matti Kähäri
3 Pia Isomäki The Function and Phenotype of Synovial Mononuclear Cells in Rheumatoid Arthritis: Regulation by Cytokines Juha Punnonen and Paavo Toivonen
1996
2 Tapani Vihinen Mouse Syndecan-1 Gene. Characterization of the Genomic Structure, the Entire Nucleotide Sequence and the Transcriptional Regulation Markku Jalkanen
1 Kenth Henriksen Regulation of Apoptosis during Spermatogenesis Martti Parvinen